PLACENTAL ABNORMALITIES AND PREECLAMPSIA IN TRISOMY 13 PREGNANCIES

Placental Abnormalities and Preeclampsia in Trisomy 13 Pregnancies

Placental Abnormalities and Preeclampsia in Trisomy 13 Pregnancies

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Women who are carrying Lie On Float a trisomy 13 fetus are prone to have an abnormal placenta as well as to develop preeclampsia in the second and third trimesters.This article provides a comprehensive review of placental abnormalities, such as small placental volume, reduced placental vascularization, a partial molar appearance of the placenta and placental mesenchymal dysplasia, and preeclampsia associated with trisomy 13 pregnancies.The candidate preeclampsia-causing genes on chromosome 13, such as sFlt1, COL4A2 CHERRY PLUM and periostin, are discussed.

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